羟酰谷胱甘肽水解酶蛋白抗体
规格：1mg/1ml
英文名： HAGH
别名： GLO2; GLX II; Glyoxalase II; HAGH; HAGH1; Hydroxyacyl glutathione hydrolase; Hydroxyacylglutathione hydrolase, mitochondrial; GLO2_HUMAN.
分子量： 32kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HAGH
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：
羟酰谷胱甘肽水解酶蛋白抗体产品介绍：background: The glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP). Glyoxalase I and Gyloxalase II (also designated hydroxyacyl glutathione hydrolase or HAGH) are members of the Gyloxalase family. The Gyloxalase II enzyme is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form reduced glutathione and D-lactic acid. It exists only as a monomer and binds two zinc ions per subunit. Glyoxalase II contains 260 amino acids. It is detected in the mitochondria and cytosol of mammals. Both Glyoxalase I and Gyloxalase II are detected at a higher activity level in breast cancer tissues than with羟酰谷胱甘肽水解酶蛋白抗体 matched unaffected tissues. This suggests that glyoxalase inhibitor drugs may be effective in the treatment of cancer. Function: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. Subunit: Monomer. Subcellular Location: Isoform 1: Mitochondrion matrix. Isoform 2: Cytoplasm. Tissue Specificity: Expressed in liver and kidney. Similarity:羟酰谷胱甘肽水解酶蛋白抗体 Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. Gene ID: 3029 Database links: Entrez Gene: 3029 Human Entrez Gene: 14651 Mouse Entrez Gene: 24439 Rat Omim: 138760 Human SwissProt: Q16775 Human SwissProt: Q99KB8 Mouse SwissProt: O35952 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
羟酰谷胱甘肽水解酶蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 新陈代谢 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid