9号染色体开放阅读框95抗体
规格：1mg/1ml
英文名： C9orf95/NRK
别名： bA235O14.2; C9orf95; Chromosome 9 open reading frame 95; FLJ20559; Nicotinamide riboside kinase 1; Nicotinic acid riboside kinase 1; NmR-K 1; NRK 1; NRK1; NRK1_HUMAN; Ribosylnicotinamide kinase 1; Rib
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C9orf95
交叉反应：Human, Mouse, Rat, Dog, Pig, Sheep,
细胞定位：
9号染色体开放阅读框95抗体产品介绍：background: Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor involved in fundamental processes in cell metabolism. NRK1 (Nicotinamide riboside kinase 1), also known as Ribosylnicotinamide kinase 1, is a 199 amino acid enzyme is involved in the synthesis of NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor. Nicotinamide riboside has been idenitifed as a nutrient in milk, suggesting that it is a useful compound for elevating the NAD+ levels in humans. NRK1 also phosphorylates the anti-cancer drugs tiazofurin and 3-deazaguanosine, which converts them into toxic NAD+ analogs and leads to the inhibition of9号染色体开放阅读框95抗体 guanine nucleotide biosynthesis. There are two isoforms of NRK1 that are produced as a result of alternative splicing events. Function: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 9号染色体开放阅读框95抗体3-deazaguanosine. Subunit: Monomer. Similarity: Belongs to the uridine kinase family. NRK subfamily. Gene ID: 54981 Database links: Entrez Gene: 54981 Human Entrez Gene: 499330 Rat Omim: 608704 Human SwissProt: Q9NWW6 Human SwissProt: Q6AY91 Rat Unigene: 494186 Human Unigene: 19716 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
9号染色体开放阅读框95抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid