睫状神经营养因子受体α抗体
规格：1mg/1ml
英文名： CNTF Receptor alpha
别名： CNTFR Alpha; Ciliary neurotrophic factor receptor alpha; CNTFR Alpha; CNTFR; Ciliary neurotrophic factor receptor alpha; Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CNTFR Al
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞膜
睫状神经营养因子受体α抗体产品介绍：background: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]. Function: Binds to CNTF. The alpha subunit provides the receptor specificity. Subunit: Heterotrimer睫状神经营养因子受体α抗体 of the alpha subunit, LIFR and IL6ST. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Nervous system and skeletal muscle. Similarity: Belongs to the type I cytokine receptor family. Type 3 subfamily. Contains 2 fibronectin type-III domains. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Gene ID: 1271 Database links: Entrez Gene: 442941 Dog Entrez Gene: 1271 睫状神经营养因子受体α抗体Human Entrez Gene: 12804 Mouse Entrez Gene: 313173 Rat Omim: 118946 Human SwissProt: Q71DR4 Dog SwissProt: P26992 Human SwissProt: O88507 Mouse SwissProt: Q08406 Rat Unigene: 129966 Human Unigene: 425178 Mouse Unigene: 55036 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神经生物学相关蛋白（Neurobiology） CNTFRα是CNTF的特异性结合蛋白。在周围神经损伤后CNTF与其受体有其特异的变化模式及调节机制，对神经损伤后的再生有重要作用。
睫状神经营养因子受体α抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid