22号染色体开放阅读框29抗体
规格：1mg/1ml
英文名： C22orf29
别名： C22orf29; CV029_HUMAN; Uncharacterized protein C22orf29.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C22orf29
交叉反应：Human,
细胞定位：
22号染色体开放阅读框29抗体产品介绍：background: ?Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 22号染色体开放阅读框29抗体9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf29 gene product has been provisionally 22号染色体开放阅读框29抗体designated C22orf29 pending further characterization Function: Could induce apoptosis in a BH3 domain-dependent manner.The direct interaction network of Bcl-2 family members may play akey role in modulation BOP intrinsic apoptotic signaling activity. Subunit: Interacts (via BH3 domain) with VDAC1. Interacts withpro-survival Bcl-2 family members, BCL2, BCL2L1 isoform Bcl-X(L),MCL1, BCL2A1 and BCL2L2. Interacts with BAX and BAK. Subcellular Location: Mitochondrion. Tissue Specificity: Ubiquitously expressed. Database links: Entrez Gene: 79680 Human SwissProt: Q7L3V2 Human Unigene: 105642 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
22号染色体开放阅读框29抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid