酪氨酸酶相关蛋白2抗体
规格:1mg/1ml
英文名: TRP2
别名: L dopachrome tautomerase; DCT; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase, tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Del
分子量: 61kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TRP2
交叉反应:Human, Mouse, Rat, Pig, Rabbit, Sheep,
细胞定位:细胞膜
酪氨酸酶相关蛋白2抗体产品介绍:background: TRP2(tyrosinase related protein 2) involved in regulating eumelanin and phaeomelanin levels. [FUNCTION] Involved in regulating eumelanin and phaeomelanin levels. [CATALYTIC ACTIVITY] L-dopachrome; 5,6-dihydroxyindole-2-carboxylate. [COFACTOR] Binds 2 zinc ions per subunit. [SUBUNIT] Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex. [SUBCELLULAR LOCATION] Melanosome membrane; Single-pass type I membrane protein. [TISSUE SPECIFICITY] Melanocytes and retinal pigmented epithelium. Function: Involved in regulating eumelanin and phaeomelanin levels. Subunit: Tyrosinase, TYRP1 and TYRP2 may酪氨酸酶相关蛋白2抗体 form a multienzyme complex. Subcellular Location: Melanosome membrane; Single-pass type I membrane protein. Melanocytes and retinal pigmented epithelium. Tissue Specificity: Melanocytes and retinal pigmented epithelium. Similarity: Belongs to the tyrosinase family. Gene ID: 1638 Database links: Entrez Gene: 1638 Human Entrez Gene: 13190 Mouse Omim: 191275 Human SwissProt: P40126 Human 酪氨酸酶相关蛋白2抗体SwissProt: P29812 Mouse Unigene: 301865 Human Unigene: 19987 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解(Synthesis and Degradation) 酪氨酸酶相关蛋白-2(tyrosinase related protein-2,TRP-2)又称多巴色素互变异构酶,是一种胞质抗原,与白癜风的病理机制有关.
酪氨酸酶相关蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 神经生物学 激酶和磷酸酶 合成与降解
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid