EXOC2蛋白抗体
规格：1mg/1ml
英文名： EXOC2
别名： EX3L1_HUMAN; Exoc3l1; Exocyst complex component 3-like protein; FLJ35539; FLJ35587; Protein Jiangli
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EXOC2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞浆
EXOC2蛋白抗体产品介绍：background: ExoC3L is a 746 amino acid protein that belongs to the SEC6 family. Localizing to the cytoplasmic and secretory vesicle, ExoC3L colocalizes with insulin granules and interacts with ExoC2, ExoC4 and ExoC5. Acting as part of the exocyst, ExoC3L may function in the regulation of insulin granule exocytosis and is expressed in insulin-secreting MIN6 cells, as well as various tissues including brain and pancreatic islets. The gene encoding ExoC3L maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% EXOC2蛋白抗体of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: As part of the exocyst, EXOC2蛋白抗体may play a role in regulated exocytosis of insulin granules. Subcellular Location: Cytoplasmic vesicle； secretory vesicle. Colocalizes with insulin granules. Similarity: Belongs to the SEC6 family. Gene ID: 283849 Database links: Entrez Gene: 283849 Human Omim: 614117 Human SwissProt: Q86VI1 Human Unigene: 647356 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EXOC2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid