A型钾离子通道调节蛋白4抗体
规格：1mg/1ml
英文名： KCNIP4
别名： A type potassium channel modulatory protein 4; a-type potassium channel modulatory protein 4; CALP; calsenilin like protein; Calsenilin-like protein; HGNC:30083; KCHIP 4; KCHIP4; KCIP4_HUMAN; KCNIP 4;
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCNIP4
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞膜
A型钾离子通道调节蛋白4抗体产品介绍：background: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have beenA型钾离子通道调节蛋白4抗体 identified for this gene. [provided by RefSeq, Jul 2008] Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a A型钾离子通道调节蛋白4抗体calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Subcellular Location: Cell membrane. Tissue Specificity: Predominantly expressed in brain. Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. Database links: Entrez Gene: 614299 Cow Entrez Gene: 80333 Human Entrez Gene: 80334 Mouse Entrez Gene: 259243 Rat Omim: 608182 Human SwissProt: Q2KI69 Cow SwissProt: Q6PIL6 Human SwissProt: Q6PHZ8 Mouse SwissProt: Q99MG9 Rat Unigene: 655705 Human Unigene: 160172 Mouse Unigene: 205864 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
A型钾离子通道调节蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid