CD39样蛋白2/ENTPD6抗体
规格:1mg/1ml
英文名: ENTPD7
别名: DKFZp667O124; Ectonucleoside triphosphate diphosphohydrolase 7; ENTPD 7; ENTPD7; ENTP7_HUMAN; LALP 1; LALP1; Lysosomal apyrase like protein 1; NTPDase 7; NTPDase7.
分子量: 69kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ENTPD7
交叉反应:Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位:
CD39样蛋白2/ENTPD6抗体产品介绍:background: LALP1 is a 604 amino acid multi-pass membrane protein that belongs to the GDA1/CD39 NTPase family. Preferentially hydrolyzing nucleoside 5’-triphosphates, LALP1 and has an order of activity with respect to possible substrates, which is UTP > GTP > CTP. The gene that encodes LALP1 consists of approximately 51,740 bases and maps to human chromosome 10q24.2. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. Function: The ENTPD7CD39样蛋白2/ENTPD6抗体 belongs to the GDA1/CD39 NTPase family and the gene resides on chromosome 10q23-q24 and contains 12 exons and 11 introns covering a genomic region of approximately 46 kilobase pairs. The subcellular localization and enzymatic activity of ENTPD7 indicated that ENTPD7 is indeed an endo-apyrase with substrate preference for nucleoside triphosphates UTP, GTP, and CTP. SubcellularCD39样蛋白2/ENTPD6抗体 Location: Cytoplasmic intracellular multi-pass membrane protein. Localizes to vesicular compartments. Similarity: Belongs to the GDA1/CD39 NTPase family. Gene ID: 57089 Database links: Entrez Gene: 57089 Human Entrez Gene: 93685 Mouse Entrez Gene: 309390 Rat SwissProt: Q9NQZ7 Human SwissProt: Q3TCT4 Mouse Unigene: 716513 Human Unigene: 296789 Mouse Unigene: 169265 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD39样蛋白2/ENTPD6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid