内质网金属肽1抗体
规格：1mg/1ml
英文名： FXNA
别名： Endoplasmic reticulum metallopeptidase 1 aminopeptidase Fxna; bA207C16.3 (novel protein similar to predicted yeast, plant and worm proteins); bA207C16.3; Endoplasmic reticulum metallopeptidase 1; ERMP
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FXNA
交叉反应：Human, Mouse, Rat, Dog, Pig, Sheep,
细胞定位：
内质网金属肽1抗体产品介绍：background: Metallopeptidases are enzymes that catalyze the hydrolysis of peptide bonds and are essential to normal physiological processes, including tissue remodeling, reproduction and embryonic development. FXNA (felix-ina), also known as ERMP1 (endoplasmic reticulum metallopeptidase 1) or KIAA1815, is a 904 amino acid metallopeptidase that belongs to the peptidase M28 protein family. FXNA is a multi-pass membrane protein that localizes to the endoplasmic reticulum membrane. FXNA binds two zinc ions and, within the ovary, is essential to the organization of oocytes and somatic cells into discrete follicular structures. The gene that encodes FXNA maps to human 内质网金属肽1抗体chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female内质网金属肽1抗体 with a male X,Y genotype. Function: Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Belongs to the peptidase M28 family. Gene ID: 79956 Database links: Entrez Gene: 79956 Human Omim: 611156 Human SwissProt: Q7Z2K6 Human Unigene: 591078 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内质网金属肽1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid