ELMOD1蛋白抗体
规格：1mg/1ml
英文名： ELMOD1
别名： DKFZp547C176; ELMD1_HUMAN; ELMO domain containing 1; ELMO domain-containing protein 1; ELMO/CED 12 domain containing 1; Elmod1.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ELMOD1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
ELMOD1蛋白抗体产品介绍：background: ELMOD1 is a 334 amino acid protein that contains one ELMO domain and is encoded by a gene that maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ELMOD1蛋白抗体ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.ELMOD1蛋白抗体 Function: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Similarity: Contains 1 ELMO domain. Gene ID: 55531 Database links: Entrez Gene: 55531 Human Entrez Gene: 768233 Cow Entrez Gene: 270162 Mouse Entrez Gene: 315670 Rat SwissProt: Q0IIE6 Cow SwissProt: Q8N336 Human SwissProt: Q3V1U8 Mouse Unigene: 495779 Human Unigene: 259791 Mouse Unigene: 13823 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ELMOD1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid