EIF2D蛋白抗体
规格：1mg/1ml
英文名： EIF2D
别名： Eukaryotic translation initiation factor 2D; HCA56; Hepatocellular carcinoma associated antigen 56; Hepatocellular carcinoma-associated antigen 56; LGTN; LIGA_HUMAN; Ligatin; OTTHUMP00000034537; OTTHU
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human EIF2D
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞膜
EIF2D蛋白抗体产品介绍：background: HCA56 is a 584 amino acid peripheral membrane protein belonging to the ligatin family. Expressed during embryonic development and in early differentiated states, ligatin is a trafficking receptor for phosphoglycoproteins. Ligatin localizes to phosphoglycoproteins within endosomes and at the cell periphery where it participates in specific metabolic processes as well as intercellular adhesion. Involved in RNA binding and translation initiation through its single PUA domain and SUI1 domain, ligatin is down-regulated with long-lastingEIF2D蛋白抗体 effects by the activation of Ca2+ dependent N-methyl-D-aspartate (NMDA) subclass of excitatory amino acid (EAA) receptors. Ligatin is considered a marker protein for membrane-vesicle transport systems. Ligatin exists as two alternatively splice variants and is encoded by a gene located on human chromosome 1. Function: Trafficking receptor for phosphoglycoproteins. Localizes phosphoglycoproteins withinEIF2D蛋白抗体 endosomes and at the cell periphery where they participate in specific metabolic processes as well as intercellular adhesion. Subcellular Location: Membrane. Similarity: Belongs to the ligatin family. Contains 1 PUA domain. Contains 1 SUI1 domain. Gene ID: 1939 Database links: Entrez Gene: 1939 Human Omim: 151625 Human SwissProt: P41214 Human Unigene: 497581 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EIF2D蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 转运蛋白 细胞粘附分子 细胞分化 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid