DMRTA2蛋白抗体
规格：1mg/1ml
英文名： DMRTA2
别名： DMRT A2; DMRT like family A2; DMRT5; DMRTA 2; dmrta2; DMTA2_HUMAN; Doublesex- and mab-3-related transcription factor 5; Doublesex- and mab-3-related transcription factor A2.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DMRTA2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞核
DMRTA2蛋白抗体产品介绍：background: DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatousDMRTA2蛋白抗体 polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: May be involved in sexual development. Subcellular Location: Nucleus. Tissue Specificity: Expressed in testis. Similarity: Belongs to the DMRT family. Contains 1 DM DNA-binding DMRTA2蛋白抗体domain. Gene ID: 63950 Database links: Entrez Gene: 63950 Human Entrez Gene: 242620 Mouse Entrez Gene: 313471 Rat SwissProt: Q5TFQ3 Human SwissProt: Q96SC8 Human SwissProt: A2A9A2 Mouse Unigene: 334481 Human Unigene: 32825 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DMRTA2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid