ATP依赖RNA解旋酶DDX55抗体
规格：1mg/1ml
英文名： INTS7/C1orf73
别名： INTS7; 5930412E23Rik; DKFZP434B168; C1orf73; Chromosome 1 open reading frame 73; chunp6916; DKFZp434B168; FLJ10736; FLJ12447; Int7; INT7_HUMAN; integrator complex subunit 7; INTS7; Ints7 integrator co
分子量： 107kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human INTS7/C1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞核
ATP依赖RNA解旋酶DDX55抗体产品介绍：background: This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Function: ATP依赖RNA解旋酶DDX55抗体Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase. SubunitATP依赖RNA解旋酶DDX55抗体: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with NABP2. Subcellular Location: Nucleus. Chromosome. Localizes to sites of DNA damage in a H2AX-independent manner. Similarity: Belongs to the Integrator subunit 7 family. Gene ID: 25896 Database links: Entrez Gene: 25896 Human Entrez Gene: 421374 Chicken Omim: 611350 Human SwissProt: Q5ZL91 Chicken SwissProt: Q1RMS6 Cow SwissProt: Q9NVH2 Human Unigene: 369285 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP依赖RNA解旋酶DDX55抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid