CXXC型锌指蛋白4抗体
规格：1mg/1ml
英文名： CXXC4
别名： CXXC finger 4; CXXC finger protein 4; CXXC type zinc finger protein 4; CXXC-type zinc finger protein 4; Cxxc4; CXXC4_HUMAN; Dvl binding protein IDAX (inhibition of the Dvl and Axin complex); IDAX; Inh
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CXXC4
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆
CXXC型锌指蛋白4抗体产品介绍：background: Idax is a 198 amino acid cytoplasmic protein that functions as a negative regulator of the Wnt signaling pathway through its interaction with the PDZ domain of Dvl-1. Containing one CXXC-type zinc finger, Idax is expressed at high levels in brain, with lower levels in testis and thymus. The gene encoding Idax maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded CXXC型锌指蛋白4抗体glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: Acts as a negative regulator of the Wnt signaling pathway CXXC型锌指蛋白4抗体via its interaction with DVL1. Subcellular Location: Cytoplasm. Similarity: Contains 1 CXXC-type zinc finger. Gene ID: 80319 Database links: Entrez Gene: 80319 Human Entrez Gene: 319478 Mouse Entrez Gene: 83824 Rat SwissProt: Q9H2H0 Human SwissProt: Q6NXI8 Mouse SwissProt: Q9EQC9 Rat Unigene: 12248 Human Unigene: 224814 Mouse Unigene: 442744 Mouse Unigene: 457442 Mouse Unigene: 209562 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CXXC型锌指蛋白4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 锌指蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid