碳水化合物磺基转移酶10抗体
规格：1mg/1ml
英文名： CHST10
别名： Carbohydrate sulfotransferase 10; CHST10; CHSTA_HUMAN; EC 2.8.2.-; HNK-1 sulfotransferase; HNK-1ST; HNK1ST; huHNK-1ST; MGC17148; OTTHUMP00000203188.
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHST10
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
碳水化合物磺基转移酶10抗体产品介绍：background: This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011] Function: Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in 碳水化合物磺基转移酶10抗体cell interactions during ontogenetic development and in synaptic plasticity in the *****. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In *****, it is highly expressed in brain, testis, ovary,碳水化合物磺基转移酶10抗体 expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe. Similarity: Belongs to the sulfotransferase 2 family. Gene ID: 9186 Database links: Entrez Gene: 9486 Human Entrez Gene: 98388 Mouse Entrez Gene: 140568 Rat Omim: 606376 Human SwissProt: O43529 Human SwissProt: Q6PGK7 Mouse SwissProt: O54702 Rat Unigene: 516370 Human Unigene: 731724 Human Unigene: 260054 Mouse Unigene: 11224 Rat hide Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碳水化合物磺基转移酶10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid