棕榈酰化膜蛋白7抗体
规格:1mg/1ml
英文名: MPP7
别名: FLJ32798; MAGUK p55 subfamily member 7; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7; Palmitoylated membrane protein 7.
分子量: 65kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MPP7
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
棕榈?;さ鞍?抗体产品介绍:background: The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like. MPP7 (MAGUK p55 subfamily member 7), also known as palmitoylated membrane protein 7, is a 576 amino acid protein that belongs to the MAGUK family and assists in the assembly of protein complexes. A periphera棕榈酰化膜蛋白7抗体 membrane protein that exists as a heterodimer, MPP7 enhances tight junction formation and epithelial cell polarity. MPP7 contains one SH3 domain, a guanylate kinase-like domain, two L27 domains and a single PDZ (DHR) domain. The gene encoding MPP7 maps to human chromosome 10p11.23 Function: MPP7 is a membrane-associated guanylate kinases (MAGUKs), which are important adaptor proteins 棕榈?;さ鞍?抗体involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. Subcellular Location: Cell Membrane; peripheral membrane protein Gene ID: 143098 Database links: Entrez Gene: 143098 Human Entrez Gene: 75739 Mouse Entrez Gene: 307035 Rat Omim: 610973 Human SwissProt: Q5T2T1 Human SwissProt: Q8BVD5 Mouse SwissProt: Q5U2Y3 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
棕榈?;さ鞍?抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid