生长抑素受体3抗体
规格：1mg/1ml
英文名： SSTR3
别名： somatostatin receptor 3; OTTHUMP00000028737; Smstr3; Somatostatin receptor 3; Somatostatin receptor subtype 3; Smstr 3; SS 3R; SS-3-R; SS3-R; SSR-28; SSR3_HUMAN; Sst3; SSTR 3; Somatostatin receptor ty
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SSTR3 C-
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：
生长抑素受体3抗体产品介绍：background: This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein生长抑素受体3抗体 coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Function: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note=Internalized 生长抑素受体3抗体into endoplasmic vesicles upon somatostatin-stimulation. Tissue Specificity: Brain, pituitary and pancreas. Post-translational modifications: Phosphorylated. Phosphorylation increases upon somatostatin binding. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 6753 Database links: Entrez Gene: 6753 Human Omim: 182453 Human SwissProt: P32745 Human Unigene: 225995 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 是一种连接G-蛋白的受体,主要分布在脑和胰腺。目前有学者用于肿瘤方面的研究。
生长抑素受体3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-100 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid