WDR68蛋白抗体
规格：1mg/1ml
英文名： WDR68
别名： AN11; Dcaf7; DCAF7_HUMAN; DDB1- and CUL4-associated factor 7; HAN11; Human anthocyanin; Petunia; Seven WD repeat protein of the AN11 family 1; SWAN 1; WD repeat domain 68; WD repeat protein An11 homol
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human WDR68
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞核 细胞浆
WDR68蛋白抗体产品介绍：background: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. Function: Involved in craniofacial development.WDR68蛋白抗体 Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. Subunit: Interacts with DYRK1A, DYRK1B and DIAPH1. Interacts with DDB1. Interacts with ZNF703. Subcellular Location: Cytoplasm. Nucleus. WDR68蛋白抗体Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm. Post-translational modifications: Protein modification; protein ubiquitination. Similarity: Belongs to the WD repeat DCAF7 family. Contains 4 WD repeats. Database links: Entrez Gene: 10238 Human Entrez Gene: 71833 Mouse Entrez Gene: 303602 Rat Omim: 605973 Human SwissProt: P61962 Human SwissProt: P61963 Mouse Unigene: 410596 Human Unigene: 307455 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
WDR68蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid