RUSC2抗体
规格：1mg/1ml
英文名： RUSC2
别名： RUSC2_HUMAN; Iporin; Interacting protein of Rab1; RUN and SH3 domain-containing protein 2.
分子量： 161kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RUSC2
交叉反应：Human, Mouse, Rat, Horse, Rabbit, Sheep,
细胞定位：细胞浆
RUSC2抗体产品介绍：background: RUSC2 is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions. RUSC2 is encoded by a gene located human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human RUSC2抗体genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Subunit: RUSC2抗体Interacts with active RAB1A and RAB1B, and with GOLGA2. Subcellular Location: Cytoplasm; cytosol. Cytosolic punctate distribution. Also observed in the perinuclear region. Tissue Specificity: Widely expressed, with highest levels in brain and testis. Similarity: Contains 1 RUN domain. Contains 1 SH3 domain. Database links: Entrez Gene: 9853 Human Omim: 611053 Human SwissProt: Q8N2Y8 Human Unigene: 493796 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RUSC2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid