G蛋白偶联受体19/GPCR GPR4抗体
规格:1mg/1ml
英文名: GPR19/GPR4
别名: GPCR GPR4;G protein coupled receptor 19; G protein coupled receptor 4; G-protein coupled receptor 19; G-protein coupled receptor 4; GPR 4; GPR19; GPR4; GPR4_HUMAN; Probable G protein coupled receptor
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human G protei
交叉反应:Human,
细胞定位:
G蛋白偶联受体19/GPCR GPR4抗体产品介绍:background: G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteinsG蛋白偶联受体19/GPCR GPR4抗体 are integral seven-pass membrane proteins with some conserved amino acid regions. GPR19, an orphan receptor, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of ***** mouse brain, including the olfactory bulb, the hippocampus, hypothalamic nuclei and the cerebellum. The GPR19 gene maps to a location on chromosome G蛋白偶联受体19/GPCR GPR4抗体12, which is a frequent target for rearrangement in cancer cells and involved in childhood acute lymphoblastic leukemia (ALL). Function: Orphan receptor. Subcellular Location: Cell membrane. Tissue Specificity: Abundant expression in the brain. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 2842 Database links: Entrez Gene: 2842 Human Omim: 602927 Human SwissProt: Q15760 Human Unigene: 657862 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体19/GPCR GPR4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid