鸟嘌呤核苷酸结合蛋白2抗体
规格：1mg/1ml
英文名： GNL2
别名： Autoantigen NGP-1; Autoantigen NGP1; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein; FLJ40906; GNL2; Guanine nucleotide binding protein-like 2 (nucleolar); HUMAUANTIG; NGP1; NOG
分子量： 84kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GNL2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
鸟嘌呤核苷酸结合蛋白2抗体产品介绍：background: GNL2 is a nucleolar guanasine-triphosphate binding protein that is ubiquitously expressed at low levels in almost all tissues. GNL2 is involved in the crucial process of trafficking proteins out of the nucleus. Specifically, it is a GTPase that interacts with the 60s preribosomal subunit in the nucleus and facilitates export of the subunit into the cytoplasm. GTPases are responsible for the hydrolysis of GTP by way of a protein region dubbed the G domain. GTPases are often involved in the translocating proteins through membranes gleaning energy for the activity by hydrolizing GTP. GNL2 shares G domain homology and some functionality with nucleostemin (GNL3), 鸟嘌呤核苷酸结合蛋白2抗体another nuclear GTPase. Highest expression of GNL2 is found in testis. Function: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Subcellular Location: Nucleus; nucleolus. Tissue Specificity: Ubiquitously expressed at relatively low levels in all human tissues tested, with the highest level of expression in the testes. Similarity: 鸟嘌呤核苷酸结合蛋白2抗体Belongs to the MMR1/HSR1 GTP-binding protein family. NOG2 subfamily. Contains 1 G (guanine nucleotide-binding) domain. Database links: UniProtKB/Swiss-Prot: Q13823.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
鸟嘌呤核苷酸结合蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白偶联受体 表观遗传学 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid