配子生成素抗体
规格：1mg/1ml
英文名： GGN
别名： FLJ35713; Gametogenetin; MGC33369; GGN_HUMAN.
分子量： 67kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GGN/Game
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：
配子生成素抗体产品介绍：background: Gametogenetin is a 652 amino acid protein that is primarily expressed in testis and ovary. Interacting with POG (proliferation of germ cells), GGNBP1 and LCRG1, gametogenetin is likely involved in spermatogenesis. Gametogenetin exists as three alternatively spliced isoforms commonly known as gametogenetin protein 1 (GGN1), gametogenetin protein 2 (GGN2) and gametogenetin protein 3 (GGN3), which localize to nuclear membrane, cytoplasm and nucleus/nucleoli, respectively. GGN1 contains two transmembrane domains配子生成素抗体 in its N-terminal half and 2 C-terminal arginine- and lysine-rich nucleolar targeting sequences. GGN1 and GGN3 are likely linked to germ cell development and both GGN1 and GGN2 may be involved in cell trafficking. Function: Gametogenetin gene is a germ cell specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different 配子生成素抗体proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. Subunit: Interacts with FANCL, GGNBP1 and ZNF403/GGNBP2 (By similarity). Database links: Entrez Gene: 199720 Human Entrez Gene: 243897 Mouse Entrez Gene: 292765 Rat Omim: 609966 Human SwissProt: Q86UU5 Human SwissProt: Q80WJ1 Mouse SwissProt: Q66HC8 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
配子生成素抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 干细胞 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid