β1-6 N-乙酰氨基葡萄糖转移酶2抗体
规格：1mg/1ml
英文名： GCNT2
别名： bA360O19.2; bA421M1.1; Beta 1 6 N acetylglucosaminyltransferase 2; CCAT; GCNT 2; GCNT2C; GCNT5; Glucosaminyl (N acetyl) transferase 2 I branching enzyme (I blood group); Glucosaminyl (N acetyl) transf
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GCNT2
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞浆 细胞膜
β1-6 N-乙酰氨基葡萄糖转移酶2抗体产品介绍：background: Belonging to the glycosyltransferase 14 family, GCNT2 (glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)), also known as II, N-acetylglucosaminyltransferase, IGNT, CCAT, ULG3, GCNT5, GCNT2C or NACGT1, is a 400 amino acid glycosyltransferase that localizes to the Golgi apparatus. Other members of the glycosyltransferase 14 family include GCNT1, GCNT3, GCNT4, GCNT6 and GCNT7. A single-pass type II membrane protein, GCNT2 functions as a branching enzyme known as beta-1,6-N-acetylglucosaminyltransferase, which converts fetal i antigen to ***** I antigen in erythrocytes during embryonic development. With expression levels increasing significantly during oncogenesis and development, GCNT2 is found at highest levels in ***** prostateβ1-6 N-乙酰氨基葡萄糖转移酶2抗体 and fetal brain, and is found at low levels in heart, small intestine, colon, brain, pancreas and kidney. Function: GCNT2 is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase that converts linear into branched poly-N-acetyllactosaminoglycans and is responsible for the conversion of fetal i antigen to ***** I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with ***** i blood group phenotype. Alternatively spliced transcript variants encoding 3 different isoforms have been described. Subcellular β1-6 N-乙酰氨基葡萄糖转移酶2抗体Location: Golgi apparatus membrane. Tissue Specificity: In the *****, highly expressed in prostate and to a lesser extent in small intestine and colon. Barely detected in heart, brain, kidney and pancreas. No expression in placenta, lung, liver, skeletal muscle, spleen, thymus, testis, ovary and peripheral blood leukocytes. In fetus, highly expressed in brain and to a lesser extent in lung and kidney. Barely detected in liver. Similarity: Belongs to the glycosyltransferase 14 family. Database links: UniProtKB/Swiss-Prot: Q06430.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β1-6 N-乙酰氨基葡萄糖转移酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid