谷氨酸脱羧酶样蛋白1抗体
规格：1mg/1ml
英文名： GADL1
别名： GADL1; GADL1_HUMAN; Glutamate decarboxylase like 1; Glutamate decarboxylase-like protein 1; MGC138191; OTTHUMP00000161199; OTTHUMP00000222306.
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GADL1
交叉反应：Human, Mouse, Rat,
细胞定位：
谷氨酸脱羧酶样蛋白1抗体产品介绍：background: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed谷氨酸脱羧酶样蛋白1抗体 throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events. Similarity: Belongs to the group II decarboxylase family. Gene ID: 谷氨酸脱羧酶样蛋白1抗体339896 Database links: Entrez Gene: 614548 Cow Entrez Gene: 485629 Dog Entrez Gene: 100712617 Guinea pig Entrez Gene: 100057562 Horse Entrez Gene: 339896 Human Entrez Gene: 73748 Mouse Entrez Gene: 100623700 Pig Entrez Gene: 367181 Rat SwissProt: A6QM00 Cow SwissProt: Q6ZQY3 Human SwissProt: Q80WP8 Mouse Unigene: 657052 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氨酸脱羧酶样蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid