面肩肱型肌营养**症相关蛋白FRG1抗体
规格：1mg/1ml
英文名： FRG1
别名： frg1; FRG1_HUMAN; FRG1A; FSG1; FSHD region gene 1 protein; Protein FRG1.
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FRG1
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit,
细胞定位：细胞核
面肩肱型肌营养**症相关蛋白FRG1抗体产品介绍：background: This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008]. Function: May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits. May be involved in pre-mRNA splicing. Subunit: Identified in the spliceosome面肩肱型肌营养**症相关蛋白FRG1抗体 C complex. Subcellular Location: Nucleus; Cajal body. Nucleus speckle. Nucleus; nucleolus. First expressed in Cajal bodies and nuclear speckles. As speckle expression diminishes, expression is seen in dense structures (dense fibrillar component and the granular component) of the nucleolus. Tissue Specificity: Expressed in ***** muscle, lymphocytes, fetal brain, muscle, and placenta. Similarity: Belongs to面肩肱型肌营养**症相关蛋白FRG1抗体 the FRG1 family. Database links: Entrez Gene: 2483 Human Entrez Gene: 14300 Mouse Omim: 601278 Human SwissProt: Q14331 Human SwissProt: P97376 Mouse Unigene: 203772 Human Unigene: 217312 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
面肩肱型肌营养**症相关蛋白FRG1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid