串珠状纤维结构蛋白1抗体
规格：1mg/1ml
英文名： Filensin
别名： Beaded filament structural protein 1; Beaded filament structural protein 1 filensin; BFSP1; BFSP1_HUMAN; CP115; CP94; CP95; Cytoskeletal protein, 115 KD; Filensin; Lens fiber cell beaded filament stru
分子量： 74kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Filensin
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆 细胞膜
串珠状纤维结构蛋白1抗体产品介绍：background: Filensin, also referred to as CP94, CP95, or CP97, is an eye lens fiber, membrane-associated, cytoskeletal intermediate filament (IF) protein that is required for the assembly of beaded filaments, cytoskeletal networks that are necessary for the long-term maintenance of optical clarity. Phakinin copolymerizes with Filensin to make up the filamentous structures present in the beaded filaments. Filensin is also crucial for lens development since it regulates lens fiber cell shape conformation and lens transparency. Filensin contains a C-terminal non-α-helical domain that contributes in several ways to its function. The head domain of Filensin includes a di-串珠状纤维结构蛋白1抗体arginine/aromatic amino acid motif that contains a potential protein kinase A phosphorylation site. Subunit: Associates with BFSP2. Subcellular Location: Membrane. Cytoplasm. Cytoplasm > cytoskeleton. Membrane- and cytoskeleton-associated.串珠状纤维结构蛋白1抗体 Tissue Specificity: Lens. DISEASE: Defects in BFSP1 are the cause of cataract cortical juvenile-onset (CCJO) [MIM:611391]. A juvenile-onset cataract with opacities restricted to the cortex of the lens, not involving the nucleus. Similarity: Belongs to the intermediate filament family. Database links: UniProtKB/Swiss-Prot: Q12934.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
串珠状纤维结构蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid