DNA复制相关元件结合因子抗体
规格：1mg/1ml
英文名： DREF
别名： Ac like transposable element; ALTE; BED type zinc finger domain containing protein 1; DNA replication related element binding factor; dREF homolog; hDREF; KIAA0785; Putative Ac like transposon; Putati
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DREF/ZBE
交叉反应：Human, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
DNA复制相关元件结合因子抗体产品介绍：background: This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation.DNA复制相关元件结合因子抗体 Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010] Function: Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elementsDNA复制相关元件结合因子抗体, but does not code for any transposase activity. Subunit: Homodimer (Potential). Subcellular Location: Nucleus. In granular structures. Tissue Specificity: Ubiquitously expressed at low levels. Expression is highest in skeletal muscle, heart, spleen and placenta. Similarity: Contains 1 BED-type zinc finger. Database links: Entrez Gene: 9189 Human Omim: 300178 Human SwissProt: O96006 Human Unigene: 131452 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA复制相关元件结合因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid