前列腺跨膜上皮2抗原抗体
规格：1mg/1ml
英文名： STEAP2
别名： 4921538B17Rik; AI930049; IPCA 1; IPCA1; Metalloreductase STEAP2; PCANAP 1; PCANAP1; Prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up regulated in metastatic prost
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human STEAP2
交叉反应：Human, Mouse, Rat, Pig, Cow,
细胞定位：细胞膜
前列腺跨膜上皮2抗原抗体产品介绍：background: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, 前列腺跨膜上皮2抗原抗体encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Subcellular Location: Endosome membrane. Cell membrane. Tissue Specificity: Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary. Similarity前列腺跨膜上皮2抗原抗体: Belongs to the STEAP family. Contains 1 ferric oxidoreductase domain. Database links: Entrez Gene: 504616 Cow Entrez Gene: 261729 Human Entrez Gene: 74051 Mouse Entrez Gene: 312052. Rat Omim: 605094 Human SwissProt: Q8NFT2 Human SwissProt: Q8BWB6 Mouse Unigene: 489051 Human Unigene: 274956 Mouse Unigene: 203614 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前列腺跨膜上皮2抗原抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid