锌指蛋白387抗体
规格：1mg/1ml
英文名： ZNF397
别名： 2810411K16Rik; MGC13250; Zinc finger and SCAN domain containing protein 15; Zinc finger and SCAN domain-containing protein 15; Zinc finger protein 397; Zinc finger protein 47; ZN397_HUMAN; ZNF 397; ZN
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF397
交叉反应：Human, Mouse, Rat, Dog, Rabbit, Guinea Pig,
细胞定位：细胞核 细胞浆
锌指蛋白387抗体产品介绍：background: This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. [provided by RefSeq,锌指蛋白387抗体 Oct 2009] Function: Isoform 3 acts as a DNA-dependent transcriptional repressor. Subcellular Location: Nucleus and Nucleus. Cytoplasm. Tissue Specificity: Expressed strongly in testis, moderately in skeletal muscle, pancreas and prostate, and weakly in heart, placenta, liver, kidney, spleen, thymus and small intestine. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: 锌指蛋白387抗体Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 9 C2H2-type zinc fingers. Contains 1 SCAN box domain. Database links: Entrez Gene: 506448 Cow Entrez Gene: 100735295 Guinea pig Entrez Gene: 100052677 Horse Entrez Gene: 84307 Human Entrez Gene: 69256 Mouse Entrez Gene: 100519201 Pig Entrez Gene: 100909408 Rat Omim: 609601 Human SwissProt: Q1LZ87 Cow SwissProt: Q8NF99 Human Unigene: 591061 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白387抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid