液泡蛋白分选蛋白26抗体
规格：1mg/1ml
英文名： VPS26
别名： FLJ12930; HB 58; HB58; Hbeta 58; Hbeta 58 homolog; Hbeta58; Hbeta58 homolog; hVPS 26; hVPS26; MGC94168; PEP 8A; PEP8A; Vacuolar protein sorting 26 A; Vacuolar protein sorting 26; Vacuolar protein sort
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VPS26
交叉反应：Human, Mouse, Rat, Cow, Zebrafish,
细胞定位：细胞浆
液泡蛋白分选蛋白26抗体产品介绍：background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves液泡蛋白分选蛋白26抗体 as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Subcellular Location: Cytoplasm. Endosome membrane. Similarity: Belongs to the VPS26 family. Database links: Entrez Gene: 510574液泡蛋白分选蛋白26抗体 Cow Entrez Gene: 9559 Human Entrez Gene: 30930 Mouse Entrez Gene: 361846 Rat Entrez Gene: 393881 Zebrafish Omim: 605506 Human SwissProt: Q0VD53 Cow SwissProt: O75436 Human SwissProt: P40336 Mouse SwissProt: Q6AY86 Rat SwissProt: Q6TNP8 Zebrafish Unigene: 499925 Human Unigene: 260703 Mouse Unigene: 473468 Mouse Unigene: 3673 Rat Unigene: 32886 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
液泡蛋白分选蛋白26抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 **细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid