磷脂酶patatin样域包含蛋白8抗体
规格:1mg/1ml
英文名: PNPLA8
别名: Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma;
分子量: 88kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PNPLA8
交叉反应:Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位:细胞浆
磷脂酶patatin样域包含蛋白8抗体产品介绍:background: This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Function: Calcium-independent磷脂酶patatin样域包含蛋白8抗体 phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region. Tissue Specificity: Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas.磷脂酶patatin样域包含蛋白8抗体 Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. Similarity: Contains 1 patatin domain. Database links: Entrez Gene: 50640 Human Entrez Gene: 67452 Mouse Entrez Gene: 314075 Rat Omim: 612123 Human SwissProt: Q9NP80 Human SwissProt: Q8K1N1 Mouse Unigene: 617340 Human Unigene: 732217 Human Unigene: 54126 Mouse Unigene: 23073 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷脂酶patatin样域包含蛋白8抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 心血管 细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid