液泡蛋白分选蛋白11抗体
规格：1mg/1ml
英文名： VPS11
别名： END1; HGNC:14583; hVPS11; PEP5; PP3476; RING finger protein 108; RNF108; Vacuolar protein sorting 11 (yeast homolog); Vacuolar protein sorting 11 (yeast); Vacuolar protein sorting 11 homolog (S. cerev
分子量： 108k
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VPS11
交叉反应：Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位：细胞浆
液泡蛋白分选蛋白11抗体产品介绍：background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in 液泡蛋白分选蛋白11抗体the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Function: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Subcellular Location: Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle. Tissue Specificity: Ubiquitous.液泡蛋白分选蛋白11抗体 Expression was highest in heart and low in lung. Similarity: Belongs to the VPS11 family. Contains 1 clathrin repeat. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 489374 Dog Entrez Gene: 55823 Human Entrez Gene: 71732 Mouse Entrez Gene: 315600 Rat Omim: 608549 Human SwissProt: Q9H270 Human SwissProt: Q91W86 Mouse Unigene: 234282 Human Unigene: 295013 Mouse Unigene: 2637 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
液泡蛋白分选蛋白11抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid