类肿瘤性抗原MA3抗体
规格:1mg/1ml
英文名: PNMA3
别名: MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_HUMAN.
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PNMA3
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
类肿瘤性抗原MA3抗体产品介绍:background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift 类肿瘤性抗原MA3抗体signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been类肿瘤性抗原MA3抗体 found for this gene. [provided by RefSeq, Sep 2013] Subcellular Location: Nucleus > nucleolus. Tissue Specificity: Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney. Similarity: Belongs to the PNMA family. Contains 1 CCHC-type zinc finger. Database links: Entrez Gene: 29944 Human GenBank: NP_037496 Human Omim: 300675 Human SwissProt: Q9UL41 Human Unigene: 449627 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
类肿瘤性抗原MA3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid