未分化胚胎干细胞转录因子1抗体
规格：1mg/1ml
英文名： UTF1
别名： hUTF 1; hUTF1; Undifferentiated embryonic cell transcription factor 1; UTF 1; UTF1; UTF1_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human UTF1
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞核
未分化胚胎干细胞转录因子1抗体产品介绍：background: UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64% homology with its mouse counterpart, suggesting a similar role between species. 未分化胚胎干细胞转录因子1抗体The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and未分化胚胎干细胞转录因子1抗体 porphyria. Function: Acts as a transcriptional coactivator of ATF2. Subunit: Binds to the N-terminal region of ATF2. Associates with the TFIID complex through interaction with TBP. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated. Database links: UniProtKB/Swiss-Prot: Q5T230.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
未分化胚胎干细胞转录因子1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 信号转导 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid