钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体
规格：1mg/1ml
英文名： PNCK
别名： Calcium/calmodulin dependent protein kinase type 1B; Calcium/calmodulin-dependent protein kinase type 1B; CaM KI beta; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMK1b; CaMKI beta; CaMKI-beta; EC
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PNCK
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：细胞核 细胞浆
钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体产品介绍：background: The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKI Beta (Ca2+/calmodulin-dependent protein kinase type 1B), also known as PNCK (pregnancy up-regulated non-ubiquitously expressed CaM kinase) or BSTK3, is a 343 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. Existing as multiple alternatively spliced isoforms, CaMKI Beta functions to catalyze the ATP-dependent phosphorylation of CaMKI, an event that activates CaMKI activity and may be important for Ca2+-triggered signaling cascades within the cell. The gene encoding CaMKI Beta maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体 Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1. Subcellular Location: Cytoplasm. Nucleus. Post-translational modifications: Phosphorylated by CAMKK1. Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. 钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体CaMK subfamily. Contains 1 protein kinase domain. Gene ID: 139728 Database links: Entrez Gene: 139728 Human Entrez Gene: 93843 Mouse Entrez Gene: 100360379 Rat Entrez Gene: 29660 Rat Omim: 300680 Human SwissProt: Q6P2M8 Human SwissProt: Q9QYK9 Mouse SwissProt: O70150 Rat Unigene: 436667 Human Unigene: 89564 Mouse Unigene: 11178 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙/钙调素依赖蛋白激酶1β/CaMKIβ抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit