胶浆成熟因子β抗体
规格：1mg/1ml
英文名： GMF beta
别名： Glia maturation factor beta; GMF. GMF-beta; GMFB; GMFB_HUMAN.
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GMF beta
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：
胶浆成熟因子β抗体产品介绍：background: Glia maturation factor β (GMF-β) belongs to the GMF subfamily of the larger actin-binding protein ADF family. This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been 胶浆成熟因子β抗体shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF-β being produced by the tumor cells. Function: This protein causes differentiation of brain cells, stimulation of neural regeneration,胶浆成熟因子β抗体 and inhibition of proliferation of tumor cells. Post-translational modifications: Phosphorylated; stimulated by phorbol ester. Similarity: Belongs to the actin-binding proteins ADF family. GMF subfamily. Contains 1 ADF-H domain. Database links: UniProtKB/Swiss-Prot: P60983.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胶浆成熟因子β抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid