双皮层蛋白结构域蛋白DCDC2抗体
规格：1mg/1ml
英文名： DCDC2
别名： DCDC 2; DCDC2; DCDC2_HUMAN; DCDC2A; Doublecortin domain containing 2; Doublecortin domain-containing protein 2; HGNC:18141; KIAA1154; Protein RU2S; RU2; RU2S; RU2S protein.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DCDC2
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位：
双皮层蛋白结构域蛋白DCDC2抗体产品介绍：background: The DCDC2 gene encodes the DCDC2 protein (Doublecortin-containing protein 2, RU2, RU2S) which contains two Doublecortin peptide domains similar to those in the Doublecortin gene. DCDC2 is transcribed as a “normal” gene, which results in a sense transcript (RU2S), but when it is transcribed in the opposite direction, a shorter antisense transcript (RU2AS), which is found in tumors, results. The DCDC2 protein demonstrates ubiquitous expression, whereas RU2AS expression is restricted to normal kidney, bladder, liver and testis, and to tumors of various histologic origins. The deduced DCDC2 protein contains 476 amino acids, while the RU2AS protein contains双皮层蛋白结构域蛋白DCDC2抗体 84 residues. There is a significant association between dyslexia and several SNPs within the DCDC2 gene. Function: May be involved in neuronal migration during development of the cerebral neocortex. Tissue Specificity: Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. DISEASE: Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance 双皮层蛋白结构域蛋白DCDC2抗体despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. Similarity: Contains 2 doublecortin domains. Database links: UniProtKB/Swiss-Prot: Q9UHG0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双皮层蛋白结构域蛋白DCDC2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid