跨膜蛋白18抗体
规格：1mg/1ml
英文名： Tmem18
别名： DKFZp434C1714; TMEM18; TMM18_HUMAN; Transmembrane protein 18.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Tmem18
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆 细胞膜
跨膜蛋白18抗体产品介绍：background: TMEM18 is a 140 amino acid multi-pass membrane protein that localizes to the nuclear membrane and is expressed in the brain. TMEM18 functions as a cell migration modulator which enhances the glioma-specific migration ability of neural precursor and neural stem cells.Overexpression of TMEM18 increases migration of human and murine neural stem cells, whereas跨膜蛋白18抗体 knockdown of TMEM18 mRNA reduces cellular migration. Two specific single nucleotide polymorphisms (SNPs) within the TMEM18 gene locus known as rs6548238 and rs756131 have been linked to obesity susceptibility. Function: Cell migration modulator which enhances 跨膜蛋白18抗体the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC). Subunit: Forms homooligomers, independently of the DNA-binding domain. Subcellular Location: Cytoplasm. Nucleus membrane; Multi-pass membrane protein. Similarity: Belongs to the TMEM18 family. Database links: UniProtKB/Swiss-Prot: Q96B42.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
跨膜蛋白18抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 ***病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid