乳腺癌相关蛋白1抗体
规格：1mg/1ml
英文名： BCAS1
别名： NABC1; AIBC 1; AIBC1; Amplified and overexpressed in breast cancer; BCAS 1; BCAS1; BCAS1_HUMAN; Breast carcinoma amplified sequence 1; Breast carcinoma-amplified sequence 1; Novel amplified in breast
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BCAS1 (5
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
乳腺癌相关蛋白1抗体产品介绍：background: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. 乳腺癌相关蛋白1抗体Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008] Function: Expressed in brain and prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors. Subunit: Homodimer. May interact with DYNLL1 and DYNLL2 Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in 乳腺癌相关蛋白1抗体brain and prostate, and at lowerlevels in testis, intestine and colon. Overexpressed in most breastcancer cell lines and down-regulated in some colorectal tumors. Database links: Entrez Gene: 8537 Human Omim: 602968 Human SwissProt: O75363 Human Unigene: 728940 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乳腺癌相关蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid