生长分化因子7抗体
规格：1mg/1ml
英文名： GDF7
别名： bmp12; bone morphogenetic protein 12; GDF-7; Gdf 7; GDF7_HUMAN; growth differentiation factor 7; Growth/differentiation factor 7.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GDF7 (36
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位：分泌型蛋白
生长分化因子7抗体产品介绍：background: Growth/differentiation factors (GDFs) are members of the TGF superfamily (1,2). Members of the TGF superfamily are involved in embryonic development and ***** tissue homeostasis (1). GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3). Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow,生长分化因子7抗体spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4). GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. (5). GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs (6). GDF-6 and GDF-7 are closely related to GDF-5 (6). GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1). Function: May play an active role in the motor area of the primate neocortex. Subunit: Homodimer; 生长分化因子7抗体disulfide-linked Subcellular Location: Secreted. Similarity: Belongs to the TGF-beta family. Database links: UniProtKB/Swiss-Prot: Q7Z4P5.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长分化因子7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 干细胞 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid