双氧化酶成熟因子抗体
规格：1mg/1ml
英文名： DUOXA1
别名： DOXA1_HUMAN; Dual oxidase activator 1; Dual oxidase maturation factor 1; duoxa1; NIP; Numb interacting protein; Numb-interacting protein; NUMBIP.
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUOXA1 (
交叉反应：Human, Mouse, Rat, Pig, Rabbit,
细胞定位：细胞膜
双氧化酶成熟因子抗体产品介绍：background: DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% 双氧化酶成熟因子抗体of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. Subunit: May interact with NUMB. Subcellular Location: Membrane; Multi-pass membrane protein双氧化酶成熟因子抗体 Tissue Specificity: Specifically expressed in thyroid gland. Also detected in esophagus. Similarity: Belongs to the DUOXA family. Database links: UniProtKB/Swiss-Prot: Q1HG43.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双氧化酶成熟因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid