G蛋白偶联受体FM4/神经调节肽U受体2抗体
规格：1mg/1ml
英文名： NMUR2
别名： FM4; G protein coupled receptor FM 4; G protein coupled receptor TGR 1; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; Neuromedin U receptor 2; Neuromedin-U receptor 2; NMU R2; NMU
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NMUR2 (1
交叉反应：Human, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
G蛋白偶联受体FM4/神经调节肽U受体2抗体产品介绍：background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It’s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root gangliaG蛋白偶联受体FM4/神经调节肽U受体2抗体 and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues. Function: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Subcellular Location: Cell membrane; Multi-pass membrane protein. TissueG蛋白偶联受体FM4/神经调节肽U受体2抗体 Specificity: Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 56923 Human Omim: 605108 Human SwissProt: Q9GZQ4 Human Unigene: 283093 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体FM4/神经调节肽U受体2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 细胞膜受体 G蛋白偶联受体 G蛋白信号 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid