八聚体结合转录因子6抗体
规格：1mg/1ml
英文名： 42649
别名： transcription factor 1; OCT 6; OCT 6; OCT-6; OCT-6; OCT6; OCT6; Octamer-binding protein 6; Octamer-binding transcription factor 6; OTF-6; OTF6; OTF6; PO3F1_HUMAN; POU class 3 homeobox 1; POU domain; P
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OCT6
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
八聚体结合转录因子6抗体产品介绍：background: This gene encodes a member of the organic zwitterions transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]. Function: High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium 八聚体结合转录因子6抗体(TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Cell membrane. Note=Detected in the plasma mebrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. Tissue Specificity: Widely expressed at low levels in ***** tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in八聚体结合转录因子6抗体 hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. Gene ID: 5453 Database links: Entrez Gene: 5453 Human Entrez Gene: 18991 Mouse Entrez Gene: 192110 Rat Omim: 602479 Human SwissProt: Q03052 Human SwissProt: P21952 Mouse SwissProt: P20267 Rat Unigene: 1837 Human Unigene: 297371 Mouse Unigene: 82720 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
八聚体结合转录因子6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 干细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid